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RSD
TEXT BOOK
INFORMATION

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CHRONIC PAIN
REFLEX SYMPATHETIC DYSTROPHY
PREVENTION and MANAGEMENT
H. Hooshmand, M.D.
Neurological Associates
Pain Management Center

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|
Chronic Pain: Reflex
sympathetic Dystrophy Prevention and Management
is the first book devoted to the
subject of Reflex Sympathetic Dystrophy (RSD). The book presents a new
classification for the different stages of RSD and features the most
comprehensive coverage of the literature on RSD and its related aspects.
Qualitative and quantitative differences between natural endorphins and
synthetic narcotics are described for the first time, as are long-term
follow-ups on sympathectomy patients. Other topics considered include
thermographic methods for the diagnosis of RSD, the role of ACTH in the
management of chronic pain, and comparisons between the effects of ACTH and
those of corticosteroids. The mechanism of development of RSD is clarified
through an extensive collection of drawings and anatomical pictures. The book
also explains why sympathectomy fails, but nerve block and physiotherapy is
successful in the treatment of RSD.
Chronic Pain: Reflex
Sympathetic Dystrophy Prevention and Management
is an important reference for
neurologists, neurosurgeons, physiatrists, thermographers, anesthesiologists,
orthopedic surgeons, interns, and students interested in the topic.
Features
 |
Presents a new
classification for the different stages of RSD |
 |
Features the most
comprehensive coverage of the literature on RSD and its related aspects |
 |
Describes for the first time
qualitative and quantitative differences between natural endorphins and
synthetic narcotics |
 |
Examines the role of ACTH in
the management of chronic pain |
 |
Clarifies the mechanism of
development of RSD through an extensive collection of drawings and anatomical
pictures |
 |
Explains why sympathectomy
fails, but nerve block and physiotherapy is successful in the treatment of RSD |
Contents
Introduction
 |
History of Reflex Sympathetic
Dystrophy |
 |
The Role of Sympathetic
Nervous System in Temperature Regulation |
 |
Anatomy of RSD |
 |
Pathophysiology of the Sympathetic
System |
 |
Sympathetic Nervous System
and Motor Function |
 |
Manifestations of RSD |
 |
Origins of RSD |
 |
Referred Pain and Trigger Point |
 |
Etiology of RSD |
 |
Prevention of RSD |
 |
Management of RSD |
|

|
Excerpt From:
Chronic Pain:
Reflex
Sympathetic Dystrophy Prevention and Management
|
|
Introduction
Chronic pain is being mismanaged
universally. Impatient surgeons try unsuccessfully to excise the pain.
Internists load the patient with narcotics and depressing tranquilizers.
Chiropractors try to cure everything with their fingers. Acupuncturists
shoot darts at the patients.
The inevitable failure in control of
pain is compounded by the hostile attitude of the impatient healer. The
victim suffers from magnified pain due to the side effects of "treatment".
The physician considers the patient crazy and relegates the pain
management to the psychiatrist who is not trained in the management of
pain.
Even this late in the twentieth
century, the patient has to cope with the nonsensical accusation that
"it's all in your head" where every kind of pain obviously resides.
The most misunderstood and complex
subject in medicine is the hyperpathic pain of sympathetic dystrophy.
Understanding this self-perpetuating pain- which "never stops" - requires
unbiased knowledge of physiology and pathology. Above all, it requires the
open mind of a physician who can understand that there is no dicotomy
between "psyche" and "soma", between "brain" and "mind", or between "true"
and "imagined" pain.
In contrast to somesthetic pain,
sympathetic pain terminates in the limbic system. It can be more severe
than the pain of cancer. It can be fatal: heart attack or suicide is more
common among there patients than the rest of the population. It causes
tremor, blepharospasm, flexion deformity, vasoconstriction, and severe
vascular migraine headache.
RSD is more common than previously
assumed by clinicians. Trauma is not at the top of the list of its variety
of etiologies. It may have its origin in the periphery: head, cervical
spin, trunk, or extremities. It may just as well originate in CNS: spinal
cord, brain stem, or cerebral hemispheres.
Invasive surgical treatments in the
form of sympathectomy, tractotomy, arthrodesis, or stimulative procedures
are apt to fail in the long run. Narcotics, alcohol, and almost all
benzodiazepines only exacerbate the sympathetic pain.
The physician can substantially
increase the rate of success in the control of this intractable pain by
taking advantage of early diagnosis, aggressive physiotherapy, multiple
sympathetic blocks, as well as epidural blocks and antidepressants.
The goal of this book is to review
the present knowledge regarding the understanding, prevention, and
management of the scourge of reflex sympathetic dystrophy. |
|
CHAPTER 1
History of Reflex Sympathetic
Dysfunction
History
"It would be a great thing
to understand pain in all its meanings."
Peter M. Latham
Reflex sympathetic dystrophy (RSD) is the most
unpleasant and uncomfortable form of chronic pain. It is the extreme
prototype of disabling chronic pain.
Chronic pain is the type of pain that persists
long after the original injury. Obviously, recurrent attacks of acute pain
due to new and repetitive damages from cancer or recurrent heart attack
cannot be considered chronic pain even though they may be of longstanding
duration.
It is estimated that approximately 30% of the
general population suffers from chronic pain. One third of these patients
suffers from RSD.
The chronic pain of RSD is typified by a marked
emotional connotation.
It is invariably accompanied by anxiety,
phobia, and neuropsychological
disturbances in the form of irritability,
agitation, and
depression.
Historically, chronic pain has been the subject
of clinical debate among physicians for a few centuries. Greek
philosophers considered the brain as the site of pain perception. The
first references to hyperpathic sympathetic type of pain appeared in the
literature in the late 1700s by the famous British surgeon Potts. He first
mentioned that trauma can be the source of
burning pain and
atrophy of the
extremity.
The first report of amputation for treatment of
this type of pain was by Denmark in 1813. Even though
amputation seems
to be a drastic and extreme form of treatment for RSD, even at the present
time surgeons are performing amputation for RSD accompanied by
osteoporotic fractures.
Needless to say, no RSD patient should undergo
amputation. Even multiple fractures in small bones of the foot can be
corrected without surgery. Proper physiotherapy, weight-bearing,
sympathetic blocks, etc., will always save the extremity from being
amputated. However, amputation is done because of lack of understanding
regarding the nature of RSD. It is done when all other measures have
failed and especially because of the fact that only a small percentage of
RSD patients are diagnosed in the early stages of the disease. By the time
the disease becomes advance, the pathology takes a rapidly accelerating
downhill course that may culminate in the disastrous procedure of
amputation. Amputation not only does not cure RSD, but it can be the
cause.
In 1851 the French Father of Physiology, Claude
Bernard,described the role of the sympathetic nervous system in
preservation of milieu interne. He was the first to
describe the sympathetic nervous system as being responsible for
temperature regulation of the internal balance in the body.
The first report of clear-cut pathologic
sympathetic dystrophy was made by the American neurologist, S. Weir
Mitchell,who reported for the first time the victims of sympathetic
dystrophy on the wounded soldiers of the Civil War. He colorfully called
this condition erythromelalgia, implying reddish sick pain. In 1867 he
described the condition in more detailed and called it causalgia....... |

Table of Figures
|
xiv
|
List of Tables
|
xvii
|
Acronyms
|
xviii
|
Preface
|
xix
|
Introduction
|
1
|
| CHAPTER 1:
History of Reflex Sympathetic
Dysfunction |
3
|
| History
|
3
|
| Truth is the Only Survivor
|
11
|
| CHAPTER
2:
The Role of Sympathetic Nervous System in
Temperature Regulation |
13
|
| Thermal Changes
|
14 |
| Temperature Changes in
RSD |
14 |
| Synaptic (Disuse) RSD
|
17 |
| Ephaptic (Causalgic) RSD
|
24 |
| Causes of Hot Spots
|
25 |
| CHAPTER
3:
Anatomy of RSD
|
27
|
| Chemical Structure of the
Sympathetic System |
29
|
| Chemical Anatomy
|
30
|
| Other Clinical Applications of
the Chemical Anatomy of SNS |
30
|
| Three-Bucket-Immersion Test
|
31
|
| CHAPTER
4:
Pathophysiology of the Sympathetic System
|
33
|
| Lateral (Somesthetic) System
|
33
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| Medial (Nociceptive) System
|
36
|
| Stress and RSD
|
39
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| Eustress
|
39
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| Distress
|
39
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| Pain and Stress
|
40
|
| Stress-Induced Analgesia (SIA)
|
41
|
| Life-Threatening Pain
|
41
|
| Origins of SIA and SIP
|
42
|
| Stress-Induced Pain (SIP)
|
42
|
| Chemicals Influencing
Stress-Induced Analgesia (SIA) |
42
|
| Sympathetic Mediated Pain (SMP)
|
44
|
| Somesthetic (Somatic) Pain vs.
Sympathetic Pain (SMP) |
44
|
| Manifestations of Sympathetic (Hyperpathic)
Pain |
44
|
| Origins of Sympathetic Pain
|
45
|
| RSD of Disuse
|
45
|
| Scar (Ephatic) Pain
|
45
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| Deafferentation
|
45
|
| Central Transmission of
Sympathetic Pain |
49
|
| Summary
|
49
|
| Clinical Examples of
Paleencephalic (Sympathetic) Pain |
51
|
| Modulators of Paleospinothalamic
Tract |
51
|
| CHAPTER 5:
Sympathetic Nervous System and Motor
Function |
57
|
| Treatment Applications
|
58
|
| CHAPTER 6:
Manifestations of RSD
|
59
|
| RSD of Disuse
|
59
|
| Ephaptic (Causalgic) RSD
|
60
|
| Nerve Root Contusion (Ephaptic)
|
61
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| Common Areas of Ephaptic Pain
|
62
|
| Common Ephaptic Watershed Zones
in Medical Practice |
62
|
| Causalgia
|
64
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| Causalgic Pain
|
64
|
| Major Causalgia and Motor
Dysfunction |
65
|
| CHAPTER 7:
Origins of RSD
|
67
|
| Peripheral vs. Central
Origin |
67 |
| Mechanism of RSD |
67 |
| Peripheral Mechanism
|
67 |
| Central (Spinal Cord) Mechanism
|
68 |
| Vicious Circle
|
68 |
| Central Biasing Mechanism
|
69 |
| Turbulance Phenomenon
|
69 |
| WDR
|
69 |
| Central (Brain Stem) Mechanism
|
69 |
| The Brain Stem as a Modulator of
Pain |
70 |
| The Brain Stem as a Modulator of
RSD |
70 |
| The Brain Stem as an Endocrine
Center |
71 |
| Serotonin and Norepinephrine as
Modulators of RSD in Brain Stem |
71 |
| Brain Stem and Trigeminal Nerve
|
74 |
| RSD and Migraine
|
75 |
| Brain Stem and Migraine:
Trigeminovascular Reflex |
75 |
| Trigeminovascular System and
Migraine |
76 |
| Migraine and Ischemia
|
76 |
| Substance P
|
77 |
| Substance P and Sympathetic
Ganglia |
78 |
| Substance P and Headache
|
78 |
| Substance P and CNS
|
78 |
| Role of Frontal Lobe in RSD and
Migraine |
78 |
| Limbic System, RSD, and Migraine
|
81 |
| Peripheral Cervicofacial
(Referred Pain) Migraine |
81 |
| CHAPTER 8:
Referred Pain and Trigger Point
|
83
|
| Referred Pain
|
83 |
| Trigger Point and Myofascial
Pain |
84 |
| Mechanism of Formation of
Trigger Point |
85 |
| Clinical Diagnosis of Trigger
Point |
85 |
| Craniofascial Muscles Trigger
Points |
86 |
| Cervical Spine Trigger Points
|
86 |
| Shoulder Area Trigger Points
|
86 |
| Upper Extremities Trigger Points
|
86 |
| Lower Extremities Trigger Points
|
86 |
| Clinical Significance of Trigger
Point |
87 |
| Cold Spots
|
87 |
| Trigger Point Injection
|
90 |
| CHAPTER 9:
Etiology of RSD
|
91
|
| Cervical Spine and RSD
|
91 |
| Cervical Spondylosis
|
92 |
| Treatment of Cervical
Spondylosis |
93 |
| Chronic Cervical Spine Injury
|
94 |
| Sherrington's Phenomenon
|
95 |
| Cervical Spine and Chest Pain
|
95 |
| Tremor and Cervical Spine
Pathology |
95 |
| Other Systemic Causes of RSD
|
95 |
| Idiopathic Forms of RSD
|
96 |
| Alcohol Abuse and RSD
|
96 |
| Intercostal RSD
|
98 |
| Spinal Cord RSD
|
98 |
| Electrical Injuries
|
100 |
| Diagnostic Tests for Electrical
Injuries |
101 |
| Differential Diagnosis of RSD
|
102 |
| Diseases Mistaken for RSD
|
102 |
| RSD Mistaken for Other Diseases
|
103 |
| CHAPTER 10:
Diagnosis of RSD
|
105
|
| Clinical Tests
|
105 |
| Measurement of Pain
|
105 |
| Davidoff Method
|
106 |
| Bone Scan
|
106 |
| QSART Sweat Response Test
|
107 |
| SCR
|
107 |
| CBV and LDF
|
107 |
| Norepinephrine Spillover
|
107 |
| Other Methods
|
108 |
| Use of Thermography in RSD
|
109 |
| Objective vs. Subjective Pain
|
111 |
| Reliability of Thermography
|
111 |
| CHAPTER 11:
Prevention of RSD
|
113
|
| Outline of Prevention
|
113 |
| Preventive Measures
|
114 |
| Early Diagnosis of RSD
|
115 |
| Reflex Sympathetic Dysfunction
|
115 |
| Avoidance of Alcohol
|
116 |
| Acid Rain
|
117 |
| Effect of Alcohol on Limbic
System |
117 |
| RSD and the Effect of Drugs on
the Brain Stem |
119 |
| Avoidance of Litigation
|
119 |
| CHAPTER 12:
Management of RSD
|
123
|
| Summary of Management
|
123 |
| Early Diagnosis
|
123 |
| Physiotherapy
|
125 |
| Massage
|
125 |
| Avoid Ice Pack Application
|
126 |
| Traction
|
126 |
| Hydrotherapy
|
126 |
| Discontinuation of Assistive
Devices |
126 |
| Trigger Point Injection
|
127 |
| Hot Trigger Point Injection
|
127 |
| Chemical Sympathetic Nerve Block
|
127 |
| Presynaptic
b Chemical Block |
127 |
| b
Blockers |
127 |
| a2-Blocker
|
129 |
| Calcium Channel Blockers
|
129 |
| Central a-Receptor
Chemical Blockers |
129 |
| Peripheral a1-Receptor
Chemical Blockers |
129 |
| Transcutaneous Electrical Nerve
Stimulator (TNS) |
130 |
| Diet |
131 |
| Food as a Stimulant
|
131 |
| Diet and RSD |
131 |
| Alcohol and Smoking
|
135 |
| Hormone Treatment:
Adrenocorticoids (Lazaroids) |
135 |
| Narcotics and Chronic Pain of
RSD |
136 |
| ACTH and Endorphins
|
136 |
| Endorphins and SNS
|
137 |
| ACTH in Neuropsychiatric
Disorders |
140 |
| TRH and CNS Depressants
|
143 |
| Hormones and Seizure Disorder
|
144 |
| Clinical Uses of ACTH
|
145 |
| ACTH in Treatment of Pain and
RSD |
145 |
| ACTH and Seizure Disorder
|
145 |
| ACTH Treatment of Depression in
RSD |
145 |
| Estrogens |
146 |
| Antidepressants |
146 |
| Management of Insomnia
|
147 |
| Anticonvulsants |
148 |
| Antiviral Treatment
|
149 |
| Discontinuation of Narcotics and
Benzodiazepines |
149 |
| Biofeedback (Operant Treatment)
|
150 |
| Invasive Nerve Blocks
|
151 |
| Sympathetic Ganglion Nerve
Blocks |
151 |
| Sympathetic Block for Efferent
Complications of RSD |
151 |
| Sympathetic Ganglion Block and
Motor Dysfunction of RSD |
151 |
| Dystonia |
151 |
| Regional Block |
152 |
| Fatigue and Sympathetic Nerve
Block: Orbeli Phenomenon |
152 |
| Repetitive Sympathetic Nerve
Block for Manifestations of RSD |
152 |
| Regional Blocks |
153 |
| Method |
153 |
| Invasive Treatment
|
154 |
| Sympathectomy |
154 |
| Technique |
155 |
| Results |
155 |
| Causes of Failure after
Sympathectomy |
156 |
| Morphine Pump |
160 |
| Patient-Controlled Analgesia (PCA)
|
161 |
| Conclusion |
162 |
| Recent Advances and Future
Trends |
164 |
| Early Diagnosis |
164 |
| Diagnostic Methods
|
164 |
| Other Advances in Diagnostic
Methods |
165 |
| Bone Scan |
165 |
| MRI |
165 |
| Further Advances in Etiology of
RSD |
165 |
| Cancer and RSD |
166 |
| Manifestations of Different
Stages of RSD |
166 |
| Headache and RSD |
166 |
| Dermatologic Manifestations of
RSD |
166 |
| Pregnancy and RSD |
166 |
| Shoulder Pain and RSD
|
166 |
| Regional Sympathetic Block
|
167 |
| Regitine Test |
167 |
| Other Forms of Treatment
|
167 |
| Opioid Withdrawal |
168 |
| Sympathectomy |
168 |
| Future Trends |
168 |
References
|
169
|
Index
|
189
|
| Author Index |
201 |
|

BOOK
ORDERING
INFORMATION

This book is
available from:
A CRC Company
Chronic Pain: Reflex Sympathetic Dystrophy, Prevention,
and Management
|
AUTHOR/AFFILIATION: |
Hooshang
Hooshmand, Neurological Associates, Vero Beach, Florida, USA |
| |
|
| |
|
| |
|
|
KEY FEATURES: |
 | Presents a new classification for the different
stages of RSD |
 | Features the most comprehensive coverage of the
literature on RSD and its related aspects |
 | Describes for the first time
qualitative and quantitative differences between natural endorphins and
systemic narcotics |
 | Examines the role of ACTH in the
management of chronic pain |
 | Clarifies the mechanism of
development of RSD through an extensive collection of drawings and
anatomical pictures |
 | Explains why sympathectomy fails,
but nerve block and physiotherapy is successful in the treatment of RSD |
|
| |
|
|
AUDIENCE: |
Neurologists, Neurosurgeons, Psychiatrists, Thermographers,
Anesthesiologists, Orthopedic Surgeons, Interns, Students. |
| |
|
|
SHELVING GUIDE: |
Medicine,
Clinical Science, Pain Management |
|
|
|
SHORT TOC: |
Chronic
Pain: Reflex Sympathetic Dystrophy, Prevention, and Management is devoted to
the subject of Reflex Sympathetic Dystrophy (RSD). The book classifies the
different stages of RSD and describes the qualitative and quantitative
differences between natural endorphins and synthetic narcotics. Included are
long-term follow-ups on sympathectomy patients. |
| |
|
|
CATALOG NUMBER: |
8667 |
|
PAGE/TRIM/BINDING: |
224 7 x 10
Hard Cover |
|
ESTIMATED ILLUSTRS. |
|
|
COLOR: |
|
|
B & W: |
58 |
|
ISBN: |
0849386675
|
| |
|
|
PRICE: |
$179.95 / £120.00 |
| |
|
|
PUB DATE: |
March 1993 |
|
|
|
This
book is available from: |
|
CRC Press, Inc.
|
|
200 Corporate
Blvd, N. W. |
|
Boca Raton, FL
33431 |
|
1-800-272-7737 |
|
You can order
this book on-line at:
http://www.crcpress.com |
|
e-mail:
orders@crcpress.com |

| The material on
the Neurological Associates Pain Management Center Homepage and all it's
associated, linked or reference pages is for informational and education
purposes. It is not
meant to take the place of your physician. Before starting, changing, or
stopping any treatments or medicines consult your physician.
H. Hooshmand, M.D., Neurological Associates Pain Management Center and
Associates will not be held liable for any damage or loss as a result of
information provided on this page or associated documentation. Again, this
WEB SITE is simply published as an information source and should not be
used to treat or make judgments on RSD/CRPS. All associated material on
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written permission from the owner; Copyright ©1999-2012 H. Hooshmand, M.D.
Please note: This is the
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|

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This page was last
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